The Muppets embark on a hilarious extra-terrestrial adventure in hopes of finding out about Gonzo's past, and discover that Gonzo's family members are aliens from a distant planet. Gonzo then gets a message that his relatives are coming for a visit...from outer space! But when word gets out on Miss Piggy's talk show, UFO Mania, that the friendly aliens are coming, a secret government agency led by K. Edgar Singer (Jeffrey Tambor) captures Gonzo and goes to great lengths to learn when his extra-terrestrial family will arrive. Now only the Muppets, led by Kermit and Miss Piggy, can save Gonzo and make the world safe for a friendly alien invasion.
Muppets from Space, featuring Andie MacDowell, Ray Liotta, and David Arquette, among others, is a star-studded close encounter with far-out fun!